Objective: Thigh muscle group segmentation is important for assessment of muscle anatomy, metabolic disease and aging. Many efforts have been put into quantifying muscle tissues with magnetic resonance (MR) imaging including manual annotation of individual muscles. However, leveraging publicly available annotations in MR images to achieve muscle group segmentation on single slice computed tomography (CT) thigh images is challenging. Method: We propose an unsupervised domain adaptation pipeline with self-training to transfer labels from 3D MR to single CT slice. First, we transform the image appearance from MR to CT with CycleGAN and feed the synthesized CT images to a segmenter simultaneously. Single CT slices are divided into hard and easy cohorts based on the entropy of pseudo labels inferenced by the segmenter. After refining easy cohort pseudo labels based on anatomical assumption, self-training with easy and hard splits is applied to fine tune the segmenter. Results: On 152 withheld single CT thigh images, the proposed pipeline achieved a mean Dice of 0.888(0.041) across all muscle groups including sartorius, hamstrings, quadriceps femoris and gracilis. muscles Conclusion: To our best knowledge, this is the first pipeline to achieve thigh imaging domain adaptation from MR to CT. The proposed pipeline is effective and robust in extracting muscle groups on 2D single slice CT thigh images.The container is available for public use at https://github.com/MASILab/DA_CT_muscle_seg

2D低剂量单板腹部计算机断层扫描（CT）切片可直接测量身体成分，这对于对衰老的健康关系进行定量表征至关重要。然而，由于不同年内获得的纵向切片之间的位置方差，使用2D腹部切片对人体成分变化的纵向分析具有挑战性。为了减少位置差异，我们将条件生成模型扩展到我们的C-斜肌，该模型在腹部区域进行任意轴向切片作为条件，并通过估计潜在空间的结构变化来生成定义的椎骨水平切片。对来自内部数据集的1170名受试者的实验和BTCV Miccai挑战赛的50名受试者的实验表明，我们的模型可以从现实主义和相似性方面产生高质量的图像。来自巴尔的摩纵向研究（BLSA）数据集的20名受试者的外部实验，其中包含纵向单腹部切片验证了我们的方法可以在肌肉和内脏脂肪面积方面与切片的位置方差进行协调。我们的方法提供了一个有希望的方向，将切片从不同的椎骨水平映射到目标切片，以减少单个切片纵向分析的位置差异。源代码可在以下网址获得：https：//github.com/masilab/c-slicegen。

从心脏病学到神经病学的疾病中，代谢健康越来越多地成为危险因素，身体成分的效率评估对于定量表征这些关系至关重要。 2D低剂量单切层扫描术（CT）提供了高分辨率，定量组织图，尽管视野有限。尽管在量化图像上下文时已经提出了许多潜在的分析，但尚无对低剂量单切片CT纵向变异性进行自动分割的全面研究。我们使用受监督的基于深度学习的细分和无监督的聚类方法研究了1469个巴尔的摩纵向研究（BLSA）腹部数据集的1469名纵向研究（BLSA）腹部数据集的1816片。在前两次扫描中有两年差距的1469名受试者中有300名被选出，以评估纵向变异性，其中包括类内相关系数（ICC）和变异系数（CV），以组织/器官的大小和平均强度为单位。我们表明，我们的分割方法在纵向环境中是稳定的，骰子范围为13个目标腹部组织结构的0.821至0.962。我们观察到ICC <0.5的大多数器官的较高变异性，肌肉，腹壁，脂肪和体膜的变化较低，平均ICC> 0.8。我们发现器官的变异性与2D切片的横截面位置高度相关。我们的努力铺平了定量探索和质量控制，以减少纵向分析中的不确定性。

We present a method for providing statistical guarantees on runtime safety and goal reachability for integrated planning and control of a class of systems with unknown nonlinear stochastic underactuated dynamics. Specifically, given a dynamics dataset, our method jointly learns a mean dynamics model, a spatially-varying disturbance bound that captures the effect of noise and model mismatch, and a feedback controller based on contraction theory that stabilizes the learned dynamics. We propose a sampling-based planner that uses the mean dynamics model and simultaneously bounds the closed-loop tracking error via a learned disturbance bound. We employ techniques from Extreme Value Theory (EVT) to estimate, to a specified level of confidence, several constants which characterize the learned components and govern the size of the tracking error bound. This ensures plans are guaranteed to be safely tracked at runtime. We validate that our guarantees translate to empirical safety in simulation on a 10D quadrotor, and in the real world on a physical CrazyFlie quadrotor and Clearpath Jackal robot, whereas baselines that ignore the model error and stochasticity are unsafe.

Sepsis is a deadly condition affecting many patients in the hospital. Recent studies have shown that patients diagnosed with sepsis have significant mortality and morbidity, resulting from the body's dysfunctional host response to infection. Clinicians often rely on the use of Sequential Organ Failure Assessment (SOFA), Systemic Inflammatory Response Syndrome (SIRS), and the Modified Early Warning Score (MEWS) to identify early signs of clinical deterioration requiring further work-up and treatment. However, many of these tools are manually computed and were not designed for automated computation. There have been different methods used for developing sepsis onset models, but many of these models must be trained on a sufficient number of patient observations in order to form accurate sepsis predictions. Additionally, the accurate annotation of patients with sepsis is a major ongoing challenge. In this paper, we propose the use of Active Learning Recurrent Neural Networks (ALRts) for short temporal horizons to improve the prediction of irregularly sampled temporal events such as sepsis. We show that an active learning RNN model trained on limited data can form robust sepsis predictions comparable to models using the entire training dataset.

Photo-identification (photo-id) is one of the main non-invasive capture-recapture methods utilised by marine researchers for monitoring cetacean (dolphin, whale, and porpoise) populations. This method has historically been performed manually resulting in high workload and cost due to the vast number of images collected. Recently automated aids have been developed to help speed-up photo-id, although they are often disjoint in their processing and do not utilise all available identifying information. Work presented in this paper aims to create a fully automatic photo-id aid capable of providing most likely matches based on all available information without the need for data pre-processing such as cropping. This is achieved through a pipeline of computer vision models and post-processing techniques aimed at detecting cetaceans in unedited field imagery before passing them downstream for individual level catalogue matching. The system is capable of handling previously uncatalogued individuals and flagging these for investigation thanks to catalogue similarity comparison. We evaluate the system against multiple real-life photo-id catalogues, achieving mAP@IOU[0.5] = 0.91, 0.96 for the task of dorsal fin detection on catalogues from Tanzania and the UK respectively and 83.1, 97.5% top-10 accuracy for the task of individual classification on catalogues from the UK and USA.

Graph neural networks (GNNs) have recently emerged as a promising learning paradigm in learning graph-structured data and have demonstrated wide success across various domains such as recommendation systems, social networks, and electronic design automation (EDA). Like other deep learning (DL) methods, GNNs are being deployed in sophisticated modern hardware systems, as well as dedicated accelerators. However, despite the popularity of GNNs and the recent efforts of bringing GNNs to hardware, the fault tolerance and resilience of GNNs has generally been overlooked. Inspired by the inherent algorithmic resilience of DL methods, this paper conducts, for the first time, a large-scale and empirical study of GNN resilience, aiming to understand the relationship between hardware faults and GNN accuracy. By developing a customized fault injection tool on top of PyTorch, we perform extensive fault injection experiments to various GNN models and application datasets. We observe that the error resilience of GNN models varies by orders of magnitude with respect to different models and application datasets. Further, we explore a low-cost error mitigation mechanism for GNN to enhance its resilience. This GNN resilience study aims to open up new directions and opportunities for future GNN accelerator design and architectural optimization.

Automated machine learning (AutoML) algorithms have grown in popularity due to their high performance and flexibility to adapt to different problems and data sets. With the increasing number of AutoML algorithms, deciding which would best suit a given problem becomes increasingly more work. Therefore, it is essential to use complex and challenging benchmarks which would be able to differentiate the AutoML algorithms from each other. This paper compares the performance of four different AutoML algorithms: Tree-based Pipeline Optimization Tool (TPOT), Auto-Sklearn, Auto-Sklearn 2, and H2O AutoML. We use the Diverse and Generative ML benchmark (DIGEN), a diverse set of synthetic datasets derived from generative functions designed to highlight the strengths and weaknesses of the performance of common machine learning algorithms. We confirm that AutoML can identify pipelines that perform well on all included datasets. Most AutoML algorithms performed similarly without much room for improvement; however, some were more consistent than others at finding high-performing solutions for some datasets.

互动主义模型引入了一种动态的语言，交流和认知方法。在这项工作中，我们在对话对话系统（SDS）的对话建模的背景下探讨了这一基本理论。为了扩展这样的理论框架，我们提出了一组设计原则，这些设计原则遵守中央心理语言和交流理论，以实现SDS中的互动主义。通过这些，关键思想可以构成我们提出的设计原则的基础。

ICECUBE是一种用于检测1 GEV和1 PEV之间大气和天体中微子的光学传感器的立方公斤阵列，该阵列已部署1.45 km至2.45 km的南极的冰盖表面以下1.45 km至2.45 km。来自ICE探测器的事件的分类和重建在ICeCube数据分析中起着核心作用。重建和分类事件是一个挑战，这是由于探测器的几何形状，不均匀的散射和冰中光的吸收，并且低于100 GEV的光，每个事件产生的信号光子数量相对较少。为了应对这一挑战，可以将ICECUBE事件表示为点云图形，并将图形神经网络（GNN）作为分类和重建方法。 GNN能够将中微子事件与宇宙射线背景区分开，对不同的中微子事件类型进行分类，并重建沉积的能量，方向和相互作用顶点。基于仿真，我们提供了1-100 GEV能量范围的比较与当前ICECUBE分析中使用的当前最新最大似然技术，包括已知系统不确定性的影响。对于中微子事件分类，与当前的IceCube方法相比，GNN以固定的假阳性速率（FPR）提高了信号效率的18％。另外，GNN在固定信号效率下将FPR的降低超过8（低于半百分比）。对于能源，方向和相互作用顶点的重建，与当前最大似然技术相比，分辨率平均提高了13％-20％。当在GPU上运行时，GNN能够以几乎是2.7 kHz的中位数ICECUBE触发速率的速率处理ICECUBE事件，这打开了在在线搜索瞬态事件中使用低能量中微子的可能性。